SLC2A9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC2A9 mutation is significantly associated with the RNA expression of many other genes, with 232 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC2A9-associated genes across cancer lineages are TEX48, BPY2, and BPY2B. Each is linked with SLC2A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A9-to-partner and partner-to-SLC2A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX48 grouped by SLC2A9-low versus SLC2A9-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A9→partner) and Y-score (partner→SLC2A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaTEX48 →+0.047+5.060<.001.00131
CNSBPY2 →+0.017+4.169<.001.00831
CNSBPY2B →+0.017+4.169<.001.00831
CNSBPY2C →+0.017+4.169<.001.00831
CNSKIR2DS4 →+0.039+3.643<.001.00731
LARGE_INTESTINEASPN →+0.034+2.841.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 232 associations by consensus.

TEX48 by SLC2A9 expression — BLOOD_Leukemia

Box plot of TEX48 in SLC2A9-low vs SLC2A9-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration