SLC2A8

Across TCGA patient cohorts, SLC2A8 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A8-associated genes across cancer lineages are JNK_pT183_Y185, P-Cadherin, and Di-Ras3. Each is linked with SLC2A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A8-to-partner and partner-to-SLC2A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by SLC2A8-low versus SLC2A8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A8→partner) and Y-score (partner→SLC2A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.194	-2.999	.017	.035	3	1
UCEC	P-Cadherin →	-0.185	-3.571	.007	.002	3	1
UCEC	Di-Ras3 →	-0.198	-3.169	.005	.019	3	1
UCEC	eIF4E →	+0.225	+3.000	.027	.036	2	1
UCEC	4E-BP1 →	+0.348	+3.029	.007	.018	2	1
UCEC	Collagen-VI →	-0.216	-2.459	.030	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

JNK_pT183_Y185 by SLC2A8 expression — UCEC

Explore this box plot interactively →