SLC2A8

Across TCGA cell cohorts, SLC2A8 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC2A8-associated genes across cancer lineages are BPIFA1, GSG1L2, and WFDC6. Each is linked with SLC2A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A8-to-partner and partner-to-SLC2A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFA1 grouped by SLC2A8-low versus SLC2A8-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A8→partner) and Y-score (partner→SLC2A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFA1 →	+0.129	+3.688	.002	.002	3	1
LARGE_INTESTINE	GSG1L2 →	+0.013	+4.022	<.001	.006	3	1
LUNG_NSCLC_LUAD	WFDC6 →	+0.050	+4.887	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	USP17L8 →	+0.005	+4.357	<.001	.006	3	1
BLOOD_Lymphoma	PVALB →	+0.428	+3.523	<.001	.009	3	1
BLOOD_Lymphoma	USP26 →	+0.163	+4.058	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

BPIFA1 by SLC2A8 expression — LARGE_INTESTINE

Explore this box plot interactively →