SLC2A2

Across TCGA patient cohorts, SLC2A2 mutation is significantly associated with the RNA expression of many other genes, with 4,150 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A2-associated genes across cancer lineages are SKA1, CYCSP49, and ZNF843. Each is linked with SLC2A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC2A2-to-partner and partner-to-SLC2A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKA1 grouped by SLC2A2-low versus SLC2A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A2→partner) and Y-score (partner→SLC2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKA1 →	+0.726	+2.180	<.001	<.001	3	4
BLCA	CYCSP49 →	+0.452	+3.527	<.001	<.001	3	3
SKCM	ZNF843 →	-0.411	-2.655	.008	.006	3	3
UCEC	R3HDM1 →	+0.353	+2.095	.003	.003	3	3
UCEC	MRTO4 →	+0.322	+2.264	.003	.001	3	3
UCEC	ENO1 →	+0.479	+2.016	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,150 associations by consensus.

SKA1 by SLC2A2 expression — UCEC

Explore this box plot interactively →