SLC2A2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC2A2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC2A2-associated genes across cancer lineages are IFNA17, CNGA2, and GALP. Each is linked with SLC2A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A2-to-partner and partner-to-SLC2A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA17 grouped by SLC2A2-low versus SLC2A2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A2→partner) and Y-score (partner→SLC2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYIFNA17 →+0.020+5.807<.001.00131
BLOOD_LeukemiaCNGA2 →+0.099+5.539<.001.00331
BLOOD_LeukemiaGALP →+0.068+5.201<.001.00631
LARGE_INTESTINELILRB2 →+0.020+4.095<.001.00931
LARGE_INTESTINEOR1Q1 →+0.279+4.684<.001.00231
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

IFNA17 by SLC2A2 expression — OVARY

Box plot of IFNA17 in SLC2A2-low vs SLC2A2-high samples in OVARY.

Explore this box plot interactively →

Exploration