SLC2A1

Across TCGA patient cohorts, SLC2A1 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A1-associated genes across cancer lineages are NF2, Caspase-7-cleavedD198, and EGFR_pY1068. Each is linked with SLC2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A1-to-partner and partner-to-SLC2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NF2 grouped by SLC2A1-low versus SLC2A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A1→partner) and Y-score (partner→SLC2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NF2 →	+0.292	+2.000	.002	.032	3	2
UCEC	Caspase-7-cleavedD198 →	+1.150	+3.479	<.001	.002	3	2
UCEC	EGFR_pY1068 →	-0.294	-2.459	.009	.019	3	1
UCEC	A-Raf_pS299 →	-0.178	-2.321	<.001	.034	3	1
UCEC	GATA6 →	-0.205	-2.693	.003	.006	3	1
UCEC	Heregulin →	-0.149	-3.156	.007	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

NF2 by SLC2A1 expression — UCEC

Explore this box plot interactively →