SLC2A1

Across TCGA cell cohorts, SLC2A1 mutation is significantly associated with the drug of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC2A1-associated genes across cancer lineages are Trametinib, AZD5991, and Quizartinib. Each is linked with SLC2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A1-to-partner and partner-to-SLC2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Trametinib grouped by SLC2A1-low versus SLC2A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A1→partner) and Y-score (partner→SLC2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Trametinib →	-0.713	-2.745	.023	.047	3	1
LARGE_INTESTINE	AZD5991 →	+0.931	+2.871	.009	.021	3	1
LARGE_INTESTINE	Quizartinib →	+0.441	+2.874	.003	.021	3	1
LARGE_INTESTINE	Masitinib →	+0.423	+2.874	.038	.021	3	1
LARGE_INTESTINE	CI-1033 →	+0.602	+2.874	.036	.021	3	1
LARGE_INTESTINE	Torin 2 →	+0.510	+2.877	.046	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Trametinib by SLC2A1 expression — LARGE_INTESTINE

Explore this box plot interactively →