SLC29A4

Across TCGA cell cohorts, SLC29A4 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC29A4-associated genes across cancer lineages are OR5A1, FAM47C, and RXFP3. Each is linked with SLC29A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC29A4-to-partner and partner-to-SLC29A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5A1 grouped by SLC29A4-low versus SLC29A4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC29A4→partner) and Y-score (partner→SLC29A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR5A1 →	+0.020	+6.022	<.001	.001	3	2
SKIN	FAM47C →	+0.006	+4.977	<.001	.007	3	2
BLOOD_Lymphoma	RXFP3 →	+0.026	+4.714	<.001	.002	3	2
SKIN	CSN2 →	+0.104	+5.415	<.001	.004	3	1
SKIN	OR1L3 →	+0.029	+5.415	<.001	.004	3	1
SKIN	SPINK9 →	+0.058	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

OR5A1 by SLC29A4 expression — SKIN

Explore this box plot interactively →