SLC29A1

Across TCGA patient cohorts, SLC29A1 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC29A1-associated genes across cancer lineages are Notch1, ATM, and Cyclin-B1. Each is linked with SLC29A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC29A1-to-partner and partner-to-SLC29A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by SLC29A1-low versus SLC29A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC29A1→partner) and Y-score (partner→SLC29A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.122	+3.335	.027	.005	3	2
UCEC	ATM →	-0.591	-2.000	<.001	.010	3	2
UCEC	Cyclin-B1 →	+0.679	+2.502	.002	.002	3	2
UCEC	eIF4E →	+0.193	+1.750	.019	.049	3	1
UCEC	GATA6 →	-0.131	-3.155	.030	.018	3	1
UCEC	Heregulin →	-0.109	-2.986	.024	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Notch1 by SLC29A1 expression — UCEC

Explore this box plot interactively →