SLC27A5

Across TCGA patient cohorts, SLC27A5 mutation is significantly associated with the RNA expression of many other genes, with 3,710 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A5-associated genes across cancer lineages are RNASEH2A, SLC25A4, and POC1A. Each is linked with SLC27A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC27A5-to-partner and partner-to-SLC27A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASEH2A grouped by SLC27A5-low versus SLC27A5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A5→partner) and Y-score (partner→SLC27A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNASEH2A →	+0.455	+3.497	.007	.002	3	3
UCEC	SLC25A4 →	+0.450	+2.711	.006	.003	3	3
UCEC	POC1A →	+0.633	+3.923	.001	<.001	3	3
UCEC	MRPL16 →	+0.301	+2.650	.009	.005	3	3
UCEC	RAD51 →	+0.989	+2.673	<.001	<.001	3	3
UCEC	RNU1-17P →	+0.194	+2.170	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,710 associations by consensus.

RNASEH2A by SLC27A5 expression — SKCM

Explore this box plot interactively →