SLC27A5

Across TCGA patient cohorts, SLC27A5 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A5-associated genes across cancer lineages are Caspase-8, FoxM1, and Rab11. Each is linked with SLC27A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A5-to-partner and partner-to-SLC27A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-8 grouped by SLC27A5-low versus SLC27A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A5→partner) and Y-score (partner→SLC27A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-8 →	-0.310	-3.973	.002	<.001	3	2
UCEC	FoxM1 →	+0.292	+1.906	.005	.016	3	2
UCEC	Rab11 →	-0.136	-2.321	.020	.033	3	2
UCEC	Rab25 →	-0.500	-3.584	<.001	.002	3	2
UCEC	Tuberin →	+0.395	+2.594	<.001	.006	3	2
UCEC	C-Raf →	+0.215	+2.700	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Caspase-8 by SLC27A5 expression — UCEC

Explore this box plot interactively →