SLC27A5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC27A5 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC27A5-associated genes across cancer lineages are GPR101, SUPT20HL1, and OR5M8. Each is linked with SLC27A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A5-to-partner and partner-to-SLC27A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR101 grouped by SLC27A5-low versus SLC27A5-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A5→partner) and Y-score (partner→SLC27A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYGPR101 →+0.016+4.990<.001.00132
OVARYSUPT20HL1 →+0.092+4.807<.001.00332
CNSOR5M8 →+0.022+5.754<.001.00231
CNSFGF3 →+0.081+4.981<.001.00831
OVARYELSPBP1 →+0.140+4.029.005.00931
OVARYSTH →+0.101+4.228.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

GPR101 by SLC27A5 expression — OVARY

Box plot of GPR101 in SLC27A5-low vs SLC27A5-high samples in OVARY.

Explore this box plot interactively →

Exploration