SLC27A1

Across TCGA patient cohorts, SLC27A1 mutation is significantly associated with the RNA expression of many other genes, with 1,426 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A1-associated genes across cancer lineages are TRAJ31, CCL8, and KISS1R. Each is linked with SLC27A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC27A1-to-partner and partner-to-SLC27A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ31 grouped by SLC27A1-low versus SLC27A1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A1→partner) and Y-score (partner→SLC27A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRAJ31 →	+0.874	+2.348	<.001	.008	3	3
COAD	CCL8 →	+1.590	+3.196	<.001	.009	3	2
COAD	KISS1R →	+0.743	+3.361	<.001	.004	3	2
COAD	SLAMF8 →	+1.277	+3.335	<.001	.005	3	2
COAD	TXNL4AP1 →	+0.226	+3.629	<.001	<.001	3	2
READ	BPNT2P →	+0.148	+6.681	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,426 associations by consensus.

TRAJ31 by SLC27A1 expression — COAD

Explore this box plot interactively →