SLC26A7

Across TCGA patient cohorts, SLC26A7 mutation is significantly associated with the RNA expression of many other genes, with 2,673 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A7-associated genes across cancer lineages are ZWINT, HROB, and RPAIN. Each is linked with SLC26A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC26A7-to-partner and partner-to-SLC26A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZWINT grouped by SLC26A7-low versus SLC26A7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A7→partner) and Y-score (partner→SLC26A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZWINT →	+0.623	+2.662	<.001	<.001	3	3
LUAD	HROB →	+0.544	+3.505	.009	.002	3	3
UCEC	RPAIN →	+0.366	+2.223	<.001	.001	3	3
UCEC	SCO1 →	+0.373	+2.061	.001	<.001	3	3
UCEC	FANCI →	+0.523	+2.072	<.001	<.001	3	3
UCEC	KIF2C →	+0.550	+2.828	.005	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,673 associations by consensus.

ZWINT by SLC26A7 expression — UCEC

Explore this box plot interactively →