SLC26A7

Across TCGA patient cohorts, SLC26A7 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A7-associated genes across cancer lineages are Tuberin_pT1462, IGFBP2, and IRS1. Each is linked with SLC26A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC26A7-to-partner and partner-to-SLC26A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin_pT1462 grouped by SLC26A7-low versus SLC26A7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A7→partner) and Y-score (partner→SLC26A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Tuberin_pT1462 →	+0.221	+2.321	.049	.033	3	3
LUAD	IGFBP2 →	-0.649	-2.321	.023	.033	3	2
LUAD	IRS1 →	+0.142	+1.762	.006	.048	3	2
LUAD	Src_pY527 →	-0.457	-3.169	.002	.018	3	2
COAD	ASNS →	+0.885	+2.815	<.001	.036	3	2
UCEC	Caspase-8 →	-0.233	-3.221	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Tuberin_pT1462 by SLC26A7 expression — SKCM

Explore this box plot interactively →