SLC26A5

Across TCGA patient cohorts, SLC26A5 mutation is significantly associated with the RNA expression of many other genes, with 3,715 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A5-associated genes across cancer lineages are INCENP, CWC27, and OIP5. Each is linked with SLC26A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC26A5-to-partner and partner-to-SLC26A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INCENP grouped by SLC26A5-low versus SLC26A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A5→partner) and Y-score (partner→SLC26A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INCENP →	+0.503	+1.660	.002	.003	3	3
UCEC	CWC27 →	+0.487	+1.807	<.001	<.001	3	3
UCEC	OIP5 →	+0.744	+2.343	<.001	<.001	3	3
UCEC	KCTD9 →	+0.524	+1.595	<.001	.001	3	3
UCEC	PSMD9 →	+0.366	+1.823	<.001	.002	3	3
UCEC	RFC5 →	+0.423	+1.856	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,715 associations by consensus.

INCENP by SLC26A5 expression — UCEC

Explore this box plot interactively →