SLC26A5

Across TCGA cell cohorts, SLC26A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,437 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC26A5-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Golgi to vacuole transport, and Fertilization. Each is linked with SLC26A5 in more than 7 cancer types. Because this analysis shows association rather than direction, both SLC26A5-to-partner and partner-to-SLC26A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by SLC26A5-low versus SLC26A5-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A5→partner) and Y-score (partner→SLC26A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.116	+0.488	<.001	.009	3	8
LUNG_SCLC	Golgi to vacuole transport →	+0.108	+0.750	<.001	<.001	3	7
OVARY	Fertilization →	-0.094	-0.097	<.001	.003	3	6
OESOPHAGUS	Cilium movement →	-0.056	-0.124	.004	.007	2	7
BONE	mRNA splice site recognition →	+0.089	+0.034	.001	.004	3	6
BLOOD_Lymphoma	Positive regulation of ruffle assembly →	+0.105	+0.087	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,437 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by SLC26A5 expression — LUNG_SCLC

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