SLC26A5

Across TCGA cell cohorts, SLC26A5 mutation is significantly associated with the RNA expression of many other genes, with 376 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC26A5-associated genes across cancer lineages are SCGB1C1, MAGEB5, and CABP2. Each is linked with SLC26A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A5-to-partner and partner-to-SLC26A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1C1 grouped by SLC26A5-low versus SLC26A5-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A5→partner) and Y-score (partner→SLC26A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SCGB1C1 →	+0.201	+4.981	<.001	.008	3	2
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
BREAST	CABP2 →	+0.408	+5.169	<.001	.005	3	1
BLOOD_Lymphoma	CRCT1 →	+0.019	+4.643	<.001	.005	3	1
BLOOD_Leukemia	WFDC11 →	+0.041	+5.539	<.001	.003	3	1
BLOOD_Leukemia	GALP →	+0.058	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 376 associations by consensus.

SCGB1C1 by SLC26A5 expression — CNS

Explore this box plot interactively →