SLC26A4-AS1

Across TCGA pan-cancer cohorts, SLC26A4-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated SLC26A4-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SLC26A4-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC26A4-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

ACC, KIRC, and UCS are the cancer types where SLC26A4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.383	0.769	<.001	103	view →
KIRC	DFS	Median	IV	0.434	0.769	<.001	92	view →
UCS	OS	Tertile	III,IV	0.205	0.742	.001	84	view →
HNSC	OS	Quartile	All	0.870	0.704	.001	65	view →
BRCA	DFS	Median	All	0.622	0.450	<.001	62	view →
MESO	OS	Tertile	All	0.495	0.240	<.001	48	view →
STAD	OS	Tertile	IV	0.694	0.240	.012	33	view →
SKCM	DFS	Median	All	0.250	0.167	.012	18	view →
BLCA	DFS	Quartile	IV	0.303	0.539	.003	17	view →
CESC	OS	Tertile	All	0.903	0.768	.007	16	view →
PRAD	DFS	Quartile	All	0.885	0.685	.004	14	view →
READ	DFS	Tertile	All	0.776	0.940	.020	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

SLC26A4-AS1–ACC (DFS)

Open the ACC breakdown →