SLC26A4-AS1

Across TCGA pan-cancer cohorts, SLC26A4-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of SLC26A4-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLC26A4-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC26A4-AS1 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and BRCA are the cancer types where SLC26A4-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC26A4-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	−0.211	<.001	12	view →
THCA	Male	III,IV	−6.532	<.001	11	view →
BRCA	Female	All	−0.564	<.001	6	view →
STAD	All	II,III,IV	−0.270	.002	6	view →
KIRP	All	All	−0.258	<.001	6	view →
COAD	All	All	−0.068	<.001	6	view →
KICH	All	All	+1.244	<.001	5	view →
READ	All	All	−0.158	.002	5	view →
LUAD	Female	All	+0.567	.002	3	view →
PRAD	All	All	+0.507	.009	2	view →
HNSC	All	II,III,IV	−0.258	.019	2	view →
BLCA	All	All	−0.183	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

SLC26A4-AS1–KIRC

Open the KIRC breakdown →