SLC26A2

Across TCGA patient cohorts, SLC26A2 mutation is significantly associated with the RNA expression of many other genes, with 3,053 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A2-associated genes across cancer lineages are DDX55, RNFT2, and KIF23. Each is linked with SLC26A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A2-to-partner and partner-to-SLC26A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DDX55 grouped by SLC26A2-low versus SLC26A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A2→partner) and Y-score (partner→SLC26A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DDX55 →	+0.428	+2.847	<.001	.001	3	2
UCEC	RNFT2 →	+0.574	+3.021	<.001	<.001	3	2
UCEC	KIF23 →	+0.644	+3.721	.001	<.001	3	2
UCEC	RANBP10 →	+0.337	+2.032	.004	.001	3	2
LUAD	RPS15AP32 →	+0.160	+4.912	<.001	.003	3	2
UCEC	RN7SL248P →	+0.050	+2.847	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,053 associations by consensus.

DDX55 by SLC26A2 expression — UCEC

Explore this box plot interactively →