SLC26A11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC26A11 mutation is significantly associated with the RNA expression of many other genes, with 2,273 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A11-associated genes across cancer lineages are RPS14P7, RNA5SP198, and SNRPGP12. Each is linked with SLC26A11 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC26A11-to-partner and partner-to-SLC26A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS14P7 grouped by SLC26A11-low versus SLC26A11-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A11→partner) and Y-score (partner→SLC26A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARPS14P7 →+0.152+5.814<.001.00133
CESCRNA5SP198 →+0.179+4.144<.001.00932
CESCSNRPGP12 →+0.215+3.542<.001.00732
READRNU6-522P →+1.151+6.681<.001<.00132
READMIR6766 →+0.644+5.039<.001.00832
CESCOR7E4P →+0.077+4.121.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,273 associations by consensus.

RPS14P7 by SLC26A11 expression — BLCA

Box plot of RPS14P7 in SLC26A11-low vs SLC26A11-high samples in BLCA.

Explore this box plot interactively →

Exploration