SLC26A11

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC26A11 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC26A11-associated genes across cancer lineages are GALNTL5, CSN2, and ZIC3. Each is linked with SLC26A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A11-to-partner and partner-to-SLC26A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALNTL5 grouped by SLC26A11-low versus SLC26A11-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A11→partner) and Y-score (partner→SLC26A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaGALNTL5 →+0.032+5.169<.001.00131
BLOOD_LymphomaCSN2 →+0.054+5.794<.001<.00131
BLOOD_LymphomaZIC3 →+0.399+5.452<.001<.00131
BLOOD_LymphomaASB11 →+0.052+4.350<.001.00531
BLOOD_LymphomaOR51Q1 →+0.123+4.927<.001.00131
BLOOD_LymphomaOR52L1 →+0.084+4.191<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

GALNTL5 by SLC26A11 expression — BLOOD_Lymphoma

Box plot of GALNTL5 in SLC26A11-low vs SLC26A11-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration