SLC26A10

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC26A10 mutation is significantly associated with the RNA expression of many other genes, with 1,930 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A10-associated genes across cancer lineages are TIMM44, SH3GL1, and MEX3D. Each is linked with SLC26A10 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC26A10-to-partner and partner-to-SLC26A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIMM44 grouped by SLC26A10-low versus SLC26A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A10→partner) and Y-score (partner→SLC26A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTIMM44 →+0.372+2.032.001.00133
UCECSH3GL1 →+0.389+2.435.001<.00133
SKCMMEX3D →+0.597+2.732.008.00333
LUADPVR →+0.758+3.205<.001.00933
UCECGTSE1 →+0.599+2.064.003.00133
UCECTXN2 →+0.392+2.488<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,930 associations by consensus.

TIMM44 by SLC26A10 expression — UCEC

Box plot of TIMM44 in SLC26A10-low vs SLC26A10-high samples in UCEC.

Explore this box plot interactively →

Exploration