SLC26A10

Across TCGA patient cohorts, SLC26A10 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A10-associated genes across cancer lineages are Tuberin_pT1462, PCNA, and TFRC. Each is linked with SLC26A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A10-to-partner and partner-to-SLC26A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin_pT1462 grouped by SLC26A10-low versus SLC26A10-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A10→partner) and Y-score (partner→SLC26A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Tuberin_pT1462 →	-0.246	-3.000	.011	.035	3	2
UCEC	PCNA →	+0.173	+1.906	.046	.016	3	2
SKCM	TFRC →	+0.850	+3.169	.005	.019	3	2
UCEC	ASNS →	+0.514	+2.584	<.001	.010	3	2
UCEC	Cyclin-B1 →	+0.609	+3.321	.007	.009	3	2
UCEC	EGFR →	-0.192	-3.169	.002	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Tuberin_pT1462 by SLC26A10 expression — LUAD

Explore this box plot interactively →