SLC26A10

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC26A10 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC26A10-associated genes across cancer lineages are LGALS13, CRYAA, and SLC36A2. Each is linked with SLC26A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A10-to-partner and partner-to-SLC26A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGALS13 grouped by SLC26A10-low versus SLC26A10-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A10→partner) and Y-score (partner→SLC26A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaLGALS13 →+0.584+4.384<.001.00631
BLOOD_LeukemiaCRYAA →+0.080+3.705<.001.00731
BLOOD_LeukemiaSLC36A2 →+0.022+3.551<.001.00931
BLOOD_LeukemiaPRSS41 →+0.055+4.060.001.00331
LUNG_NSCLC_LUADTAAR8 →+0.022+5.662<.001.00231
LUNG_NSCLC_LUADOOSP4B →+0.023+6.266<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

LGALS13 by SLC26A10 expression — BLOOD_Leukemia

Box plot of LGALS13 in SLC26A10-low vs SLC26A10-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration