SLC26A1

Across TCGA patient cohorts, SLC26A1 mutation is significantly associated with the RNA expression of many other genes, with 1,829 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A1-associated genes across cancer lineages are RNU6-78P, LINC01035, and LINC01048. Each is linked with SLC26A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A1-to-partner and partner-to-SLC26A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-78P grouped by SLC26A1-low versus SLC26A1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A1→partner) and Y-score (partner→SLC26A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-78P →	+0.287	+4.969	<.001	.004	3	2
CESC	LINC01035 →	+0.045	+4.669	<.001	.007	3	2
COAD	LINC01048 →	+0.398	+3.768	.001	.006	3	2
COAD	TRDV3 →	+0.613	+3.915	<.001	.004	3	2
CESC	MIR3908 →	+0.366	+5.345	<.001	.001	3	2
UCEC	RNU4-58P →	+0.129	+2.074	.008	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,829 associations by consensus.

RNU6-78P by SLC26A1 expression — CESC

Explore this box plot interactively →