SLC25A6P4

Across TCGA pan-cancer cohorts, SLC25A6P4 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated SLC25A6P4 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher SLC25A6P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC25A6P4 expression acts as an unfavorable survival marker, although some lineages such as ESCA and OV show a favorable association.

THCA, UVM, and LIHC are the cancer types where SLC25A6P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	II,III,IV	0.848	0.976	.001	40	view →
UVM	DFS	Tertile	III,IV	0.301	0.699	.001	32	view →
LIHC	OS	Quartile	III,IV	0.360	0.802	.001	31	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	24	view →
ESCA	DFS	Median	IV	0.634	0.205	.006	24	view →
OV	DFS	Median	All	0.189	0.131	.009	22	view →
UCS	OS	Tertile	IV	1.000	0.262	.024	18	view →
KIRP	DFS	Tertile	All	1.000	0.821	.021	13	view →
SKCM	DFS	Tertile	III,IV	0.825	0.563	.018	11	view →
THYM	DFS	Median	III,IV	1.000	0.402	.004	10	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →
DLBC	DFS	Tertile	III,IV	0.383	0.984	.043	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

SLC25A6P4–THCA (DFS)

Open the THCA breakdown →