SLC25A48

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A48 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A48-associated genes across cancer lineages are RHCG, ASB10, and CRYGC. Each is linked with SLC25A48 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A48-to-partner and partner-to-SLC25A48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RHCG grouped by SLC25A48-low versus SLC25A48-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A48→partner) and Y-score (partner→SLC25A48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaRHCG →+0.103+3.729<.001.00931
BLOOD_LeukemiaASB10 →+0.079+3.551<.001.00931
BLOOD_LeukemiaCRYGC →+0.020+4.384<.001.00631
BLOOD_LeukemiaSLC35G3 →+0.030+5.289.002<.00131
BLOOD_LeukemiaOBP2B →+0.036+4.269<.001.00231
BLOOD_LeukemiaTCP11X2 →+0.213+4.060<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

RHCG by SLC25A48 expression — BLOOD_Leukemia

Box plot of RHCG in SLC25A48-low vs SLC25A48-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration