SLC25A48

Across TCGA cell cohorts, SLC25A48 mutation is significantly associated with the mutation status of many other genes, with 608 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A48-associated genes across cancer lineages are LARP4, FMNL1, and CYP2D6. Each is linked with SLC25A48 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A48-to-partner and partner-to-SLC25A48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LARP4 grouped by SLC25A48-low versus SLC25A48-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A48→partner) and Y-score (partner→SLC25A48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LARP4 →	+4.772	+5.339	.004	.004	1	3
LUNG_NSCLC_LUAD	FMNL1 →	+4.772	+5.339	.004	.004	1	3
BLOOD_Leukemia	CYP2D6 →	+3.338	+4.083	.003	.003	1	2
BLOOD_Leukemia	STS →	+5.560	+4.736	.003	.003	1	2
BLOOD_Leukemia	NOMO1 →	+3.560	+4.247	.002	.002	1	2
BLOOD_Leukemia	HAS1 →	+3.338	+4.083	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 608 associations by consensus.

LARP4 by SLC25A48 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →