SLC25A48-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC25A48-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated SLC25A48-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher SLC25A48-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLC25A48-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and ESCA show a favorable association.

UVM, UCS, and MESO are the cancer types where SLC25A48-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileAll0.1040.858<.00199view →
UCSDFSTertileIII,IV0.7270.270<.00192view →
MESOOSTertileAll0.0840.560<.00154view →
ESCADFSTertileIV0.8260.284.03442view →
KICHOSTertileII,III,IV0.0930.841<.00136view →
TGCTDFSTertileII,III,IV0.6180.950.02536view →
COADDFSTertileAll0.2610.574.00626view →
THYMDFSTertileAll0.4130.797.01221view →
LUADDFSTertileII,III,IV0.2870.473.01118view →
LIHCOSTertileII,III,IV0.2260.769.00818view →
THCAOSTertileIV0.7201.000.00418view →
BRCADFSTertileIV0.7750.392.03017view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

SLC25A48-AS1–UVM (OS)

Kaplan–Meier survival curve for SLC25A48-AS1 RNA-high vs -low samples in UVM.

Open the UVM breakdown →

Exploration