SLC25A48-AS1

Across TCGA pan-cancer cohorts, SLC25A48-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of SLC25A48-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SLC25A48-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC25A48-AS1 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

HNSC, BRCA, and KICH are the cancer types where SLC25A48-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC25A48-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.023	.003	7	view →
BRCA	All	All	+0.076	<.001	6	view →
KICH	All	All	−0.028	<.001	6	view →
LUSC	All	All	+0.038	<.001	4	view →
UCEC	All	All	+0.026	.022	4	view →
KIRP	All	All	−0.017	.022	2	view →
READ	All	All	+0.053	.049	1	view →
LUAD	All	All	+0.040	.024	1	view →
THCA	Male	All	+0.007	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

SLC25A48-AS1–HNSC

Open the HNSC breakdown →