SLC25A44

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC25A44 mutation is significantly associated with the RNA expression of many other genes, with 2,120 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A44-associated genes across cancer lineages are BMP7-AS1, LINC02500, and LINC02272. Each is linked with SLC25A44 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A44-to-partner and partner-to-SLC25A44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMP7-AS1 grouped by SLC25A44-low versus SLC25A44-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A44→partner) and Y-score (partner→SLC25A44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCBMP7-AS1 →+0.135+3.450<.001.00532
CESCLINC02500 →+0.657+4.144<.001.00932
CESCLINC02272 →+0.071+5.584<.001.00132
CESCDNAJB6P5 →+0.212+3.684<.001.00532
CESCNF1P10 →+0.133+5.569<.001<.00132
CESCHMGB4 →+0.015+4.306<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,120 associations by consensus.

BMP7-AS1 by SLC25A44 expression — CESC

Box plot of BMP7-AS1 in SLC25A44-low vs SLC25A44-high samples in CESC.

Explore this box plot interactively →

Exploration