SLC25A44

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A44 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A44-associated genes across cancer lineages are MYF6, ZCCHC13, and KRTAP26-1. Each is linked with SLC25A44 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A44-to-partner and partner-to-SLC25A44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF6 grouped by SLC25A44-low versus SLC25A44-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A44→partner) and Y-score (partner→SLC25A44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaMYF6 →+0.156+4.705<.001.00331
BLOOD_LeukemiaZCCHC13 →+0.022+5.569<.001.00131
BLOOD_LeukemiaKRTAP26-1 →+0.009+4.969<.001.00331
BLOOD_LeukemiaSPANXN5 →+0.014+4.969<.001.00331
BLOOD_LeukemiaGRXCR1 →+0.017+5.569<.001.00131
BLOOD_LeukemiaARSF →+0.304+4.705<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MYF6 by SLC25A44 expression — BLOOD_Leukemia

Box plot of MYF6 in SLC25A44-low vs SLC25A44-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration