SLC25A43

Across TCGA patient cohorts, SLC25A43 mutation is significantly associated with the RNA expression of many other genes, with 1,236 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A43-associated genes across cancer lineages are RNA5SP422, RN7SKP2, and RNA5SP76. Each is linked with SLC25A43 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A43-to-partner and partner-to-SLC25A43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by SLC25A43-low versus SLC25A43-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A43→partner) and Y-score (partner→SLC25A43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP422 →	+0.602	+2.086	.001	.002	3	2
SKCM	RN7SKP2 →	+0.183	+4.993	<.001	.002	3	2
BRCA	RNA5SP76 →	+0.585	+7.731	<.001	.009	3	1
SKCM	FKBP4P2 →	+0.040	+5.622	<.001	<.001	3	1
SKCM	DPRXP7 →	+0.085	+5.993	<.001	.001	3	1
SKCM	GGTLC3 →	+0.143	+4.838	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,236 associations by consensus.

RNA5SP422 by SLC25A43 expression — UCEC

Explore this box plot interactively →