SLC25A43

Across TCGA cell cohorts, SLC25A43 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,302 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC25A43-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Interleukin-10-mediated signaling pathway, and Intracellular receptor signaling pathway. Each is linked with SLC25A43 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC25A43-to-partner and partner-to-SLC25A43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic pattern recognition receptor signaling pathway grouped by SLC25A43-low versus SLC25A43-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A43→partner) and Y-score (partner→SLC25A43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytoplasmic pattern recognition receptor signaling pathway →	+0.069	+2.675	<.001	<.001	3	9
BONE	Interleukin-10-mediated signaling pathway →	+0.195	+1.840	<.001	<.001	3	9
SOFT_TISSUE	Intracellular receptor signaling pathway →	+0.039	+1.275	<.001	<.001	3	8
BONE	Positive regulation of stress-activated MAPK cascade →	+0.194	+2.023	.001	<.001	2	9
BONE	Actin filament organization →	+0.148	+2.230	<.001	<.001	3	8
SOFT_TISSUE	Transforming growth factor beta1 production →	+0.265	+1.962	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,302 associations by consensus.

Cytoplasmic pattern recognition receptor signaling pathway by SLC25A43 expression — BONE

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