SLC25A43

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A43 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC25A43-associated genes across cancer lineages are OR11A1 and KRTAP4-2. Each is linked with SLC25A43 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A43-to-partner and partner-to-SLC25A43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11A1 grouped by SLC25A43-low versus SLC25A43-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A43→partner) and Y-score (partner→SLC25A43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYOR11A1 →+0.006+5.196<.001.00531
OVARYKRTAP4-2 →+0.028+5.196<.001.00531
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR11A1 by SLC25A43 expression — OVARY

Box plot of OR11A1 in SLC25A43-low vs SLC25A43-high samples in OVARY.

Explore this box plot interactively →

Exploration