SLC25A40

Across TCGA pan-cancer cohorts, SLC25A40 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SLC25A40’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SLC25A40 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types SLC25A40 is over-expressed in tumor, although a few such as CCRCC and HNSC show the opposite, repressed pattern.

LUAD, LSCC, and CCRCC are the cancer types where SLC25A40 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC25A40 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	II,III,IV	+0.236	<.001	8	view →
LSCC	Male	All	+0.182	<.001	5	view →
CCRCC	Female	II,III,IV	−0.267	.006	2	view →
HNSC	All	II,III,IV	−0.118	.042	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

SLC25A40–LUAD

Open the LUAD breakdown →