SLC25A40

Across TCGA patient cohorts, SLC25A40 mutation is significantly associated with the RNA expression of many other genes, with 149 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A40-associated genes across cancer lineages are PPP1R2P5, MIR4769, and RN7SL366P. Each is linked with SLC25A40 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A40-to-partner and partner-to-SLC25A40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R2P5 grouped by SLC25A40-low versus SLC25A40-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A40→partner) and Y-score (partner→SLC25A40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PPP1R2P5 →	+0.095	+5.273	.002	.006	3	2
SKCM	MIR4769 →	+0.736	+5.199	<.001	.003	3	2
SKCM	RN7SL366P →	+0.145	+5.624	<.001	.002	3	2
UCEC	RN7SL191P →	+0.262	+2.911	<.001	.003	3	2
BLCA	RNU2-15P →	+0.418	+7.640	<.001	.009	3	2
UCEC	TVP23CP2 →	+0.247	+2.895	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 149 associations by consensus.

PPP1R2P5 by SLC25A40 expression — LUSC

Explore this box plot interactively →