SLC25A40

Across TCGA cell cohorts, SLC25A40 protein abundance is significantly associated with the go_rna of many other GO terms, with 666 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLC25A40-associated GO terms across cancer lineages are Replication fork reversal, Mucus secretion, and Regulatory ncRNA processing. Each is linked with SLC25A40 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A40-to-partner and partner-to-SLC25A40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Replication fork reversal grouped by SLC25A40-low versus SLC25A40-high in LUNG_NSCLC_LUAD.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A40→partner) and Y-score (partner→SLC25A40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Replication fork reversal →	-0.097	-2.063	.001	.003	3	2
LUNG_NSCLC_LUAD	Mucus secretion →	-0.256	-1.972	.009	.007	3	1
LUNG_NSCLC_LUAD	Regulatory ncRNA processing →	-0.053	-2.063	.005	.003	3	1
LUNG_NSCLC_LUAD	Tubulin deacetylation →	+0.180	+2.570	.001	.004	3	1
LUNG_NSCLC_LUAD	Chromosome attachment to the nuclear envelope →	+0.245	+2.530	.009	.004	3	1
LUNG_SCLC	Transdifferentiation →	+0.355	+1.041	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 666 associations by consensus.

Replication fork reversal by SLC25A40 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →