SLC25A40

Across TCGA cell cohorts, SLC25A40 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible SLC25A40-associated genes across cancer lineages are NPVF, TCF23, and FAM216B. Each is linked with SLC25A40 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A40-to-partner and partner-to-SLC25A40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPVF grouped by SLC25A40-low versus SLC25A40-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A40→partner) and Y-score (partner→SLC25A40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	NPVF →	+0.020	+5.000	<.001	.005	3	1
KIDNEY	TCF23 →	+0.006	+5.000	<.001	.005	3	1
KIDNEY	FAM216B →	+0.103	+5.000	<.001	.005	3	1
KIDNEY	GLYATL3 →	+0.043	+5.000	<.001	.005	3	1
KIDNEY	KIR2DL3 →	+0.013	+5.000	<.001	.005	3	1
KIDNEY	KLF18 →	+0.006	+5.000	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

NPVF by SLC25A40 expression — KIDNEY

Explore this box plot interactively →