SLC25A4

Across TCGA patient cohorts, SLC25A4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,201 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC25A4-associated genes across cancer lineages are EMP3, RECQL, and KIF23. Each is linked with SLC25A4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC25A4-to-partner and partner-to-SLC25A4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A4 versus EMP3 in UCEC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A4→partner) and Y-score (partner→SLC25A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EMP3 →	-0.569	-0.539	.005	.002	3	5
UCEC	RECQL →	-0.659	-0.711	<.001	<.001	3	5
OV	KIF23 →	-0.886	-0.434	.002	<.001	3	4
OV	KIF20B →	-0.624	-0.414	.001	.002	3	4
CCRCC	ADI1 →	+0.456	+0.332	<.001	.001	3	4
GBM	TSHZ3 →	-0.578	-0.468	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,201 associations by consensus.

SLC25A4 vs EMP3 — UCEC

Explore this scatter interactively →