SLC25A39

Across TCGA pan-cancer cohorts, SLC25A39 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC25A39 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SLC25A39 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC25A39 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

COAD, UCEC, and SKCM are the cancer types where SLC25A39 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.193	0.681	.003	7	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	DFS	Median	II,III,IV	0.865	0.559	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC25A39–COAD (OS)

Open the COAD breakdown →