SLC25A37

Across TCGA patient cohorts, SLC25A37 mutation is significantly associated with the RNA expression of many other genes, with 2,188 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A37-associated genes across cancer lineages are PBK, LINC01072, and SHLD3. Each is linked with SLC25A37 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A37-to-partner and partner-to-SLC25A37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PBK grouped by SLC25A37-low versus SLC25A37-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A37→partner) and Y-score (partner→SLC25A37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PBK →	+0.944	+2.502	<.001	.001	3	3
UCEC	LINC01072 →	+0.099	+1.836	<.001	.005	3	3
UCEC	SHLD3 →	+0.554	+2.201	<.001	.001	3	3
CESC	LINC02559 →	+1.025	+5.342	<.001	.002	3	2
CESC	LINC02210-CRHR1 →	+0.140	+4.409	<.001	.006	3	2
UCEC	SNRPD3 →	+0.305	+2.108	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,188 associations by consensus.

PBK by SLC25A37 expression — UCEC

Explore this box plot interactively →