SLC25A37

Across TCGA pan-cancer cohorts, SLC25A37 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SLC25A37’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where SLC25A37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC25A37 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

KIRP, THCA, and KIRC are the cancer types where SLC25A37 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC25A37 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	III,IV	+1.431	<.001	11	view →
THCA	Male	III,IV	+0.907	<.001	9	view →
KIRC	Male	IV	+0.858	<.001	9	view →
HNSC	All	III,IV	+0.505	.001	8	view →
LUAD	All	II,III,IV	+0.751	<.001	7	view →
BRCA	All	III,IV	−1.130	<.001	6	view →
KICH	Female	All	−1.111	<.001	4	view →
READ	All	All	+0.695	.007	4	view →
CHOL	All	All	+1.236	<.001	3	view →
COAD	All	II,III,IV	+0.357	.004	3	view →
PRAD	All	All	+0.555	<.001	2	view →
LUSC	All	All	−0.332	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SLC25A37–KIRP

Open the KIRP breakdown →