SLC25A37

Across TCGA patient cohorts, SLC25A37 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A37-associated genes across cancer lineages are eIF4E, MEK1, and PDCD4. Each is linked with SLC25A37 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A37-to-partner and partner-to-SLC25A37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by SLC25A37-low versus SLC25A37-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A37→partner) and Y-score (partner→SLC25A37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.205	+3.472	.006	.002	3	2
UCEC	MEK1 →	+0.466	+2.415	<.001	.003	3	2
UCEC	PDCD4 →	-0.734	-3.459	<.001	<.001	3	2
UCEC	STAT3_pY705 →	-0.502	-2.584	<.001	<.001	3	2
UCEC	eIF4G →	+0.246	+3.321	.027	.009	3	1
UCEC	A-Raf_pS299 →	-0.132	-2.807	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

eIF4E by SLC25A37 expression — UCEC

Explore this box plot interactively →