SLC25A37

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A37 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A37-associated genes across cancer lineages are OR11H1, C1QL2, and OR4K2. Each is linked with SLC25A37 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A37-to-partner and partner-to-SLC25A37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H1 grouped by SLC25A37-low versus SLC25A37-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A37→partner) and Y-score (partner→SLC25A37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR11H1 →+0.097+5.201<.001.00631
BLOOD_LeukemiaC1QL2 →+0.012+4.922<.001.00931
BLOOD_LeukemiaOR4K2 →+0.042+5.969<.001.00131
BLOOD_LeukemiaBPIFB6 →+0.063+5.969<.001.00131
BLOOD_LeukemiaPRORY →+0.173+5.201<.001.00631
BLOOD_LeukemiaOR11G2 →+0.392+4.922<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OR11H1 by SLC25A37 expression — BLOOD_Leukemia

Box plot of OR11H1 in SLC25A37-low vs SLC25A37-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration