SLC25A34

Across TCGA patient cohorts, SLC25A34 mutation is significantly associated with the RNA expression of many other genes, with 114 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A34-associated genes across cancer lineages are MIR588, RBPJP5, and RBAK-RBAKDN. Each is linked with SLC25A34 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A34-to-partner and partner-to-SLC25A34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR588 grouped by SLC25A34-low versus SLC25A34-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A34→partner) and Y-score (partner→SLC25A34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR588 →	+0.325	+4.743	<.001	.005	3	2
SKCM	RBPJP5 →	+0.041	+6.225	<.001	<.001	3	2
UCEC	RBAK-RBAKDN →	+0.147	+2.627	<.001	.005	3	1
UCEC	INO80B-WBP1 →	+0.130	+3.477	<.001	.006	3	1
COAD	RNU6-694P →	+0.254	+4.308	.003	.009	3	1
COAD	COMMD4P2 →	+0.164	+4.942	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 114 associations by consensus.

MIR588 by SLC25A34 expression — SKCM

Explore this box plot interactively →