SLC25A34

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC25A34 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A34-associated genes across cancer lineages are ACC_pS79, P-Cadherin, and TIGAR. Each is linked with SLC25A34 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A34-to-partner and partner-to-SLC25A34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC_pS79 grouped by SLC25A34-low versus SLC25A34-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A34→partner) and Y-score (partner→SLC25A34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECACC_pS79 →+0.397+3.169.037.02031
UCECP-Cadherin →-0.201-3.156.011.02031
UCECTIGAR →+0.168+3.196.045.01011
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ACC_pS79 by SLC25A34 expression — UCEC

Box plot of ACC_pS79 in SLC25A34-low vs SLC25A34-high samples in UCEC.

Explore this box plot interactively →

Exploration