SLC25A32

Across TCGA pan-cancer cohorts, SLC25A32 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC25A32 data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC25A32 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC25A32 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

CCRCC, PDAC, and LUAD are the cancer types where SLC25A32 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	II,III,IV	0.610	1.000	.002	51	view →
PDAC	OS	Tertile	All	0.361	0.876	.001	29	view →
LUAD	OS	Median	III,IV	0.779	0.338	.011	5	view →
LSCC	DFS	Median	All	0.900	0.732	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC25A32–CCRCC (OS)

Open the CCRCC breakdown →